Emilio Perucca Selected Research

Norfenfluramine

10/2021

Fenfluramine repurposing from weight loss to epilepsy: What we do and do not know.

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Emilio Perucca Research Topics

Disease

101	Epilepsy (Aura) 01/2022 - 01/2002
51	Seizures (Absence Seizure) 01/2022 - 01/2002
15	Partial Epilepsies (Epilepsy, Partial) 01/2019 - 11/2003
12	Drug Resistant Epilepsy 12/2019 - 01/2003
11	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2022 - 04/2011
8	Lennox Gastaut Syndrome 01/2022 - 07/2008
7	Epileptic Syndromes 01/2021 - 01/2003
5	Congenital Abnormalities (Deformity) 01/2020 - 11/2005
5	Body Weight (Weight, Body) 01/2016 - 12/2003
4	Brain Diseases (Brain Disorder) 11/2020 - 01/2002
4	Absence Epilepsy (Childhood Absence Epilepsy) 01/2017 - 05/2010
3	Tuberous Sclerosis (Bourneville's Disease) 01/2022 - 01/2019
3	Status Epilepticus (Complex Partial Status Epilepticus) 06/2011 - 01/2002
2	COVID-19 11/2020 - 01/2020
2	Fatigue 09/2019 - 11/2011
2	Sleepiness 09/2019 - 11/2011
2	Cognitive Dysfunction 01/2019 - 11/2015
2	Dementia (Dementias) 01/2018 - 01/2018
2	Generalized Epilepsy 09/2015 - 10/2014
2	Spontaneous Abortion (Miscarriage) 08/2015 - 07/2011
2	Brain Neoplasms (Brain Tumor) 12/2013 - 02/2002
2	Malformations of Cortical Development 02/2008 - 04/2007
2	Schizophrenia (Dementia Praecox) 10/2006 - 08/2002
2	Craniocerebral Trauma (Head Injury) 01/2005 - 12/2004
1	Weight Loss (Weight Reduction) 10/2021
1	Fever (Fevers) 01/2021
1	Hypohidrosis 01/2021
1	Diarrhea 09/2019
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2019
1	Idiopathic Generalized Epilepsy 12/2016

Drug/Important Bio-Agent (IBA)

76	Anticonvulsants (Antiepileptic Drugs)IBA 11/2020 - 01/2002
40	Pharmaceutical PreparationsIBA 01/2022 - 01/2002
18	Valproic Acid (Depakote)FDA LinkGeneric 01/2021 - 01/2002
15	Carbamazepine (Tegretol)FDA LinkGeneric 08/2015 - 01/2002
12	Lamotrigine (Lamictal)FDA LinkGeneric 01/2016 - 01/2006
10	Levetiracetam (Keppra)FDA LinkGeneric 01/2021 - 03/2005
9	Phenobarbital (Luminal)FDA Link 08/2015 - 01/2002
8	perampanelIBA 10/2021 - 01/2013
8	Phenytoin (Dilantin)FDA LinkGeneric 03/2013 - 01/2002
6	Topiramate (Topamax)FDA LinkGeneric 01/2021 - 06/2003
5	CannabidiolIBA 01/2022 - 10/2018
5	Vigabatrin FDA Link 11/2009 - 01/2006
4	EnzymesIBA 12/2019 - 12/2003
4	Lacosamide FDA Link 11/2011 - 12/2008
3	FenfluramineIBA 01/2022 - 11/2020
3	Clobazam (HR 376)IBA 01/2021 - 09/2019
3	rufinamide FDA Link 01/2020 - 07/2008
3	Oxcarbazepine (Trileptal)FDA LinkGeneric 08/2015 - 01/2006
3	Pregabalin (Lyrica)FDA Link 08/2009 - 01/2006
3	Gabapentin (Neurontin)FDA LinkGeneric 07/2006 - 02/2003
2	CenobamateIBA 01/2022 - 11/2020
2	Ethosuximide (Zarontin)FDA LinkGeneric 01/2021 - 03/2013
2	Biomarkers (Surrogate Marker)IBA 11/2020 - 11/2015
2	SolutionsIBA 11/2020 - 10/2018
2	AcidsIBA 12/2016 - 01/2013
2	Zonisamide (Zonegran)FDA LinkGeneric 03/2013 - 01/2006
2	eslicarbazepine acetateIBA 11/2011 - 04/2011
2	Genetic Markers (Genetic Marker)IBA 04/2009 - 01/2003
2	Risperidone (Risperdal Consta)FDA LinkGeneric 10/2006 - 08/2002
1	lorcaserinIBA 01/2022
1	5-HT2C Serotonin ReceptorIBA 01/2022
1	NorfenfluramineIBA 10/2021
1	Adenosine (Adenocard)FDA LinkGeneric 01/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2021
1	Clonazepam (Rivotril)FDA LinkGeneric 01/2021
1	Prednisolone (Predate)FDA LinkGeneric 11/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2020
1	Methylprednisolone FDA LinkGeneric 11/2020
1	AutoantibodiesIBA 11/2020
1	Therapeutic UsesIBA 01/2020
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 12/2019
1	Cytochrome P-450 CYP3AIBA 12/2019
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 12/2019
1	N-desmethylclobazam (norclobazam)IBA 09/2019
1	Transaminases (Aminotransferases)IBA 09/2019
1	Memantine (Namenda)FDA Link 01/2019
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 01/2019
1	Everolimus FDA Link 01/2019
1	Sodium Channel BlockersIBA 01/2019
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2019
1	Antisense OligonucleotidesIBA 01/2019
1	Sodium Channels (Sodium Channel)IBA 01/2019
1	Ion Channels (Ion Channel)IBA 01/2019
1	NAD (NADH)IBA 01/2019
1	Peptides (Polypeptides)IBA 01/2019
1	CannabinoidsIBA 12/2017
1	AMPA Receptors (AMPA Receptor)IBA 01/2017
1	GoldIBA 01/2016

Therapy/Procedure

37	Therapeutics 01/2022 - 11/2002
5	Precision Medicine 01/2022 - 10/2015
5	Drug Therapy (Chemotherapy) 01/2016 - 07/2002
2	Ketogenic Diet 01/2019 - 02/2006
2	Vagus Nerve Stimulation 01/2019 - 06/2014
1	Ambulatory Care (Outpatient Care) 01/2020
1	Wearable Electronic Devices 01/2019
1	Psychology Biofeedback (Biofeedback) 01/2019
1	Aftercare (After-Treatment) 01/2017
1	Deep Brain Stimulation 01/2017
1	Drug Substitution 04/2016
1	Institutionalization (Institutionalized Persons) 01/2016